James E Simon Selected Research

Polyphenols

7/2023	Protective Effects of Polyphenol-Rich Extracts against Neurotoxicity Elicited by Paraquat or Rotenone in Cellular Models of Parkinson's Disease.
4/2023	Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease.
1/2021	Chemical, Manufacturing, and Standardization Controls of Grape Polyphenol Dietary Supplements in Support of a Clinical Study: Mass Uniformity, Polyphenol Dosage, and Profiles.
1/2020	A critical review on grape polyphenols for neuroprotection: Strategies to enhance bioefficacy.
12/2013	Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model.
2/2013	Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease.
4/2012	Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment.
1/2009	Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

James E Simon Research Topics

Disease

4	Parkinson Disease (Parkinson's Disease) 07/2023 - 01/2019
4	Weight Loss (Weight Reduction) 12/2021 - 01/2019
4	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2021 - 03/2010
4	Alzheimer Disease (Alzheimer's Disease) 02/2013 - 01/2009
2	Mitochondrial Diseases (Mitochondrial Disease) 07/2023 - 04/2023
2	Inflammation (Inflammations) 02/2023 - 01/2019
2	Nervous System Diseases (Neurological Disorders) 01/2019 - 04/2012
1	COVID-19 03/2023
1	Infections 03/2023
1	Neurobehavioral Manifestations 11/2021
1	Alcoholism (Alcohol Abuse) 07/2021
1	Disease Resistance 01/2021
1	Major Depressive Disorder (Major Depressive Disorders) 01/2020
1	Obesity 01/2020
1	Weight Gain 01/2019
1	Synucleinopathies 01/2019
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2013
1	Dementia (Dementias) 02/2013
1	Osteoporosis 10/2010
1	Body Weight (Weight, Body) 10/2010
1	Amyloid Plaque 03/2010
1	Arthritis (Polyarthritis) 11/2008
1	Chronic Disease (Chronic Diseases) 04/2008

Drug/Important Bio-Agent (IBA)

8	PolyphenolsIBA 07/2023 - 01/2009
4	raspberry ketoneIBA 12/2021 - 01/2019
3	AntioxidantsIBA 07/2023 - 04/2008
2	ParaquatIBA 07/2023 - 04/2023
2	RotenoneIBA 07/2023 - 04/2023
2	StilbenesIBA 07/2023 - 04/2023
2	SynucleinsIBA 11/2021 - 01/2019
2	IsoflavonesIBA 11/2021 - 10/2010
2	Proteins (Proteins, Gene)FDA Link 11/2021 - 01/2019
2	ResveratrolIBA 12/2013 - 03/2010
1	Anti-Infective Agents (Microbicides)IBA 03/2023
1	3-nitrotyrosineIBA 02/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2023
1	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)IBA 02/2023
1	dihydromyricetinIBA 07/2021
1	homoserine kinaseIBA 01/2021
1	Flavoring AgentsIBA 07/2020
1	phenolic acidIBA 01/2019
1	FlavonoidsIBA 01/2019
1	Heme Oxygenase-1IBA 01/2019
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2019
1	PrebioticsIBA 01/2019
1	AcidsIBA 01/2019
1	Grape Seed ExtractIBA 12/2013
1	proanthocyanidinIBA 04/2012
1	Amyloid beta-PeptidesIBA 03/2010
1	Peptides (Polypeptides)IBA 03/2010
1	Gallic AcidIBA 01/2009
1	TeaIBA 11/2008
1	Protective AgentsIBA 04/2008
1	Anthocyanins (Anthocyanin)IBA 04/2008

Therapy/Procedure

2	Therapeutics 11/2021 - 01/2020
1	Catheters 10/2010